Gadolinium retention within multiple rat organs after intra-articular administration of gadolinium-based contrast agents
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منابع مشابه
Linear Gadolinium-Based Contrast Agents Are Associated With Brain Gadolinium Retention in Healthy Rats
OBJECTIVES The aim of this study was to evaluate Gd retention in the deep cerebellar nuclei (DCN) of linear gadolinium-based contrast agents (GBCAs) compared with a macrocyclic contrast agent. MATERIALS AND METHODS The brain tissue retention of Gd of 3 linear GBCAs (gadobenate dimeglumine, gadopentetate dimeglumine, and gadodiamide) and a macrocyclic GBCA (gadoterate meglumine) was compared i...
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Nephrogenic systemic fibrosis (NSF), previously known as nephrogenic fibrosing dermopathy, is an emerging systemic fibrosing disorder that develops in the setting of renal insufficiency. Nephrogenic fibrosing dermopathy (NFD) is a fibrosing condition of the skin which shows an increased number of dendritic cells, fibroblasts and thickened collagen fibers resembling scleromyxedema. It is charact...
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Background MRI has dramatically changed the way we diagnose disease. With the introduction of contrast agents specifically for MRI, we were now able to see that which was ‘invisible’. Gadopentetate dimeglumine (Magnevist) was introduced over 20 years ago, since then many more agents with variable features have been introduced. Several newer agents have improved ‘relaxivity’ and some designated ...
متن کاملAre gadolinium contrast agents suitable for gadolinium neutron capture therapy?
OBJECTIVE Gadolinium neutron capture therapy (GdNCT) is a potential treatment for malignant tumors based on two steps: (1) injection of a tumor-specific (157)Gd compound; (2) tumor irradiation with thermal neutrons. The GdNC reaction can induce cell death provided that Gd is proximate to DNA. Here, we studied the nuclear uptake of Gd by glioblastoma (GBM) tumor cells after treatment with two Gd...
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ژورنال
عنوان ژورنال: Skeletal Radiology
سال: 2021
ISSN: 0364-2348,1432-2161
DOI: 10.1007/s00256-020-03695-3